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Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor
[Image: see text] Human cannabinoid type 1 (CB1) G-protein coupled receptor is a potential therapeutic target for obesity. The previously predicted and experimentally validated ensemble of ligand-free conformations of CB1 [Scott, C. E. et al. Protein Sci.2013, 22, 101−11323184890; Ahn, K. H. et al....
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| Publicado no: | J Chem Inf Model |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863456/ https://ncbi.nlm.nih.gov/pubmed/26633590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00581 |
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