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Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models

Ordinary differential equation models have become a wide-spread approach to analyze dynamical systems and understand underlying mechanisms. Model parameters are often unknown and have to be estimated from experimental data, e.g., by maximum-likelihood estimation. In particular, models of biological...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Rosenblatt, Marcus, Timmer, Jens, Kaschek, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863410/
https://ncbi.nlm.nih.gov/pubmed/27243005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00041
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