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Acute blockade of IL-25 in a colitis associated colon cancer model leads to increased tumor burden

Chronic inflammation within the gastrointestinal tract results in an increased risk for developing colorectal cancer. Epithelial cytokines, including interleukin-25 (IL-25), are produced in the colon and are critical for protection from parasites, but can also be pathogenic in the context of inflamm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thelen, Tennille D., Green, Ryan M., Ziegler, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863374/
https://ncbi.nlm.nih.gov/pubmed/27165713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25643
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