SP1 and UTE1 Decoy ODNs inhibit activation and proliferation of hepatic stellate cells by targeting tissue inhibitors of metalloproteinase 1

BACKGROUND: The excessive accumulation of extracellular matrix of hepatic fibrosis is positively correlated with tissue inhibitors of metalloproteinase 1 (TIMP1). Here we aimed to investigate whether TIMP1 may be down-regulated by Decoy ODNs strategy to capture transcriptional factor upstream TIMP1...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Jia, Dong, Ni, Yi-Ran, Zhang, Yan-Qiong, Rao, Chun, Hou, Jun, Tang, He-Qing, Liu, Chang-Bai, Wu, Jiang-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863342/
https://ncbi.nlm.nih.gov/pubmed/27175276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0094-6
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