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The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery

Lipofectamine reagents are widely accepted as “gold-standard” for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cardarelli, Francesco, Digiacomo, Luca, Marchini, Cristina, Amici, Augusto, Salomone, Fabrizio, Fiume, Giuseppe, Rossetta, Alessandro, Gratton, Enrico, Pozzi, Daniela, Caracciolo, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863168/
https://ncbi.nlm.nih.gov/pubmed/27165510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25879
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