Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System

Objective. To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS). Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked potentials and electroretinograms in conscious and a...

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Vydáno v:J Ophthalmol
Hlavní autoři: Charng, Jason, He, Zheng, Vingrys, Algis J., Fish, Rebecca L., Gurrell, Rachel, Bui, Bang V., Nguyen, Christine T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863103/
https://ncbi.nlm.nih.gov/pubmed/27239335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5801826
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