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mGluR3 Activation Recruits Cytoplasmic TWIK-1 Channels to Membrane that Enhances Ammonium Uptake in Hippocampal Astrocytes

TWIK-1 two-pore domain K(+) channels are highly expressed in mature hippocampal astrocytes. While the TWIK-1 activity is readily detectable on astrocyte membrane, the majority of channels are retained in the intracellular compartments, which raises an intriguing question of whether the membrane TWIK...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Wang, Wei, Kiyoshi, Conrad M., Du, Yixing, Ma, Baofeng, Alford, Catherine C., Chen, Haijun, Zhou, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862944/
https://ncbi.nlm.nih.gov/pubmed/26553349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9496-4
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