G protein-gated K(+) channel ablation in forebrain pyramidal neurons selectively impairs fear learning

BACKGROUND: Cognitive dysfunction occurs in many debilitating conditions including Alzheimer’s disease, Down syndrome, schizophrenia, and mood disorders. The dorsal hippocampus is a critical locus of cognitive processes linked to spatial and contextual learning. G protein-gated inwardly rectifying K...

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Publicat a:Biol Psychiatry
Autors principals: Victoria, Nicole C., de Velasco, Ezequiel Marron Fernandez, Ostrovskaya, Olga, Metzger, Stefania, Xia, Zhilian, Kotecki, Lydia, Benneyworth, Michael A., Zink, Anastasia N., Martemyanov, Kirill A., Wickman, Kevin
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862939/
https://ncbi.nlm.nih.gov/pubmed/26612516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.10.004
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