Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency

Hydrogen sulfide (H(2)S) is a gasotransmitter known to regulate bone formation and bone mass in unperturbed mice. However, it is presently unknown whether H(2)S plays a role in pathologic bone loss. Here we show that ovariectomy (ovx), a model of postmenopausal bone loss, decreases serum H(2)S level...

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Pubblicato in:J Bone Miner Res
Autori principali: Grassi, Francesco, Tyagi, Abdul Malik, Calvert, John W, Gambari, Laura, Walker, Lindsey D, Yu, Mingcan, Robinson, Jerid, Li, Jau-Yi, Lisignoli, Gina, Vaccaro, Chiara, Adams, Jonathan, Pacifici, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862919/
https://ncbi.nlm.nih.gov/pubmed/26614970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2757
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