Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease – Role of Exosomal MicroRNA Transfer

BACKGROUND: Despite the promise shown by stem cells for restoration of cardiac function following myocardial infarction (MI), the poor survival of transplanted cells has been a major issue. Hypoxia inducible factor-1 (HIF-1) is a transcription factor that mediates adaptive responses to ischemia. Her...

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Bibliografiske detaljer
Udgivet i:Circulation
Main Authors: Ong, Sang-Ging, Lee, Won Hee, Huang, Mei, Dey, Devaveena, Kodo, Kazuki, Sanchez-Freire, Veronica, Gold, Joseph D., Wu, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862832/
https://ncbi.nlm.nih.gov/pubmed/25200057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.007917
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