Linocin and OmpW Are Involved in Attachment of the Cystic Fibrosis-Associated Pathogen Burkholderia cepacia Complex to Lung Epithelial Cells and Protect Mice against Infection

Members of the Burkholderia cepacia complex (Bcc) cause chronic opportunistic lung infections in people with cystic fibrosis (CF), resulting in a gradual lung function decline and, ultimately, patient death. The Bcc is a complex of 20 species and is rarely eradicated once a patient is colonized; the...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: McClean, Siobhán, Healy, Marc E., Collins, Cassandra, Carberry, Stephen, O'Shaughnessy, Luke, Dennehy, Ruth, Adams, Áine, Kennelly, Helen, Corbett, Jennifer M., Carty, Fiona, Cahill, Laura A., Callaghan, Máire, English, Karen, Mahon, Bernard P., Doyle, Sean, Shinoy, Minu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862727/
https://ncbi.nlm.nih.gov/pubmed/26902727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01248-15
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