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Bacterial Dose-Dependent Role of G Protein-Coupled Receptor Kinase 5 in Escherichia coli-Induced Pneumonia

G protein-coupled receptor kinase 5 (GRK5) is a serine/threonine kinase previously shown to mediate polymicrobial sepsis-induced inflammation. The goal of the present study was to examine the role of GRK5 in monomicrobial pulmonary infection by using an intratracheal Escherichia coli infection model...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Packiriswamy, Nandakumar, Steury, Michael, McCabe, Ian C., Fitzgerald, Scott D., Parameswaran, Narayanan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862718/
https://ncbi.nlm.nih.gov/pubmed/26975990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00051-16
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