FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6

We previously identified a cell wall-associated protein from Fusobacterium nucleatum, a Gram-negative bacterium of the oral cavity, that induces human beta defensin 2 (hBD-2) in primary human oral epithelial cells (HOECs) and designated it FAD-I (Fusobacterium-associated defensin inducer). Here, we...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Bhattacharyya, Sanghamitra, Ghosh, Santosh K., Shokeen, Bhumika, Eapan, Betty, Lux, Renate, Kiselar, Janna, Nithianantham, Stanley, Young, Andrew, Pandiyan, Pushpa, McCormick, Thomas S., Weinberg, Aaron
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862701/
https://ncbi.nlm.nih.gov/pubmed/26930710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01311-15
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