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Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population

Hypoxia is involved in the development of chronic inflammatory processes. Under hypoxic conditions HIF1A, VEGF and VEGFR2 are expressed and mediate the course of the resultant disease. The aim of the present study was to define the associations between tSNPs in these genes and COPD susceptibility an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Baz-Dávila, Rebeca, Espinoza-Jiménez, Adriana, Rodríguez-Pérez, María del Cristo, Zulueta, Javier, Varo, Nerea, Montejo, Ángela, Almeida-González, Delia, Aguirre-Jaime, Armando, Córdoba-Lanús, Elizabeth, Casanova, Ciro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862690/
https://ncbi.nlm.nih.gov/pubmed/27163696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154998
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