Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus

Due to the stringent population bottleneck that occurs during sexual HIV-1 transmission, systemic infection is typically established by a limited number of founder viruses. Elucidation of the precise forces influencing the selection of founder viruses may reveal key vulnerabilities that could aid in...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Tully, Damien C., Ogilvie, Colin B., Batorsky, Rebecca E., Bean, David J., Power, Karen A., Ghebremichael, Musie, Bedard, Hunter E., Gladden, Adrianne D., Seese, Aaron M., Amero, Molly A., Lane, Kimberly, McGrath, Graham, Bazner, Suzane B., Tinsley, Jake, Lennon, Niall J., Henn, Matthew R., Brumme, Zabrina L., Norris, Philip J., Rosenberg, Eric S., Mayer, Kenneth H., Jessen, Heiko, Kosakovsky Pond, Sergei L., Walker, Bruce D., Altfeld, Marcus, Carlson, Jonathan M., Allen, Todd M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862634/
https://ncbi.nlm.nih.gov/pubmed/27163788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005619
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