Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection

Cell-free mitochondiral DNA (mtDNA) is an immunogenic molecule associated with many inflammatory conditions. We evaluated the relationship between cell-free mtDNA in cerebrospinal fluid (CSF) and neurocognitive performance and inflammation during HIV infection. In a cross-sectional analysis, we eval...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Pérez-Santiago, Josué, Schrier, Rachel D., de Oliveira, Michelli F., Gianella, Sara, Var, Susanna R., Day, Tyler R. C., Ramirez-Gaona, Miguel, Suben, Jesse D., Murrell, Ben, Massanella, Marta, Cherner, Mariana, Smith, Davey M., Ellis, Ronald J., Letendre, Scott L., Mehta, Sanjay R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862614/
https://ncbi.nlm.nih.gov/pubmed/26428514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-015-0384-5
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