First Report of cfr-Carrying Plasmids in the Pandemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Staphylococcal Cassette Chromosome mec Type IV Clone

Linezolid is often the drug of last resort for serious methicillin-resistant Staphylococcus aureus (MRSA) infections. Linezolid resistance is mediated by mutations in 23S rRNA and genes for ribosomal proteins; cfr, encoding phenicol, lincosamide, oxazolidinone, pleuromutilin, and streptogramin A (Ph...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Shore, Anna C., Lazaris, Alexandros, Kinnevey, Peter M., Brennan, Orla M., Brennan, Gráinne I., O'Connell, Brian, Feßler, Andrea T., Schwarz, Stefan, Coleman, David C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Mechanisms of Resistance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862533/
https://ncbi.nlm.nih.gov/pubmed/26953212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02949-15
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