Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse

Hirschsprung Disease (HSCR) is a potentially deadly birth defect characterized by the absence of the enteric nervous system (ENS) in distal bowel. Although HSCR has clear genetic causes, no HSCR-associated mutation is 100% penetrant, suggesting gene-gene and gene-environment interactions determine H...

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Détails bibliographiques
Publié dans:Dev Biol
Auteurs principaux: Schill, Ellen Merrick, Lake, Jonathan I., Tusheva, Olga A., Nagy, Nandor, Bery, Saya K., Foster, Lynne, Avetisyan, Marina, Johnson, Stephen L., Stenson, William F., Goldstein, Allan M., Heuckeroth, Robert O.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862364/
https://ncbi.nlm.nih.gov/pubmed/26586201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.09.023
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