RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border

Endothelial barrier dysfunction underlies chronic inflammatory diseases. In searching for new proteins essential to the human endothelial inflammatory response, we have found that the endosomal GTPase RhoB is up-regulated in response to inflammatory cytokines and expressed in the endothelium of some...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Marcos-Ramiro, Beatriz, García-Weber, Diego, Barroso, Susana, Feito, Jorge, Ortega, María C., Cernuda-Morollón, Eva, Reglero-Real, Natalia, Fernández-Martín, Laura, Durán, Maria C., Alonso, Miguel A., Correas, Isabel, Cox, Susan, Ridley, Anne J., Millán, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862328/
https://ncbi.nlm.nih.gov/pubmed/27138256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504038
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