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Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

INTRODUCTION: Enlargement of a pre-existing intracranial aneurysm is a well-established risk factor of rupture. Excessive low wall shear stress concomitant with turbulent flow in the dome of an aneurysm may contribute to progression and rupture. However, how stress conditions regulate enlargement of...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Aoki, Tomohiro, Yamamoto, Kimiko, Fukuda, Miyuki, Shimogonya, Yuji, Fukuda, Shunichi, Narumiya, Shuh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862234/
https://ncbi.nlm.nih.gov/pubmed/27160403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0318-3
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