Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer

BACKGROUND: Podocalyxin-like 1 (PODXL) is an anti-adhesive transmembrane protein that has been demonstrated to be an independent factor of poor prognosis in colorectal cancer (CRC). The gene encoding PODXL is located to chromosome 7, which also harbours the gene for the epidermal growth factor recep...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Larsson, Anna H., Lehn, Sophie, Wangefjord, Sakarias, Karnevi, Emelie, Kuteeva, Eugenia, Sundström, Magnus, Nodin, Björn, Uhlén, Mathias, Eberhard, Jakob, Birgisson, Helgi, Jirström, Karin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862047/
https://ncbi.nlm.nih.gov/pubmed/27160084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0882-0
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