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Treponema pallidum Lipoprotein TP0435 Expressed in Borrelia burgdorferi Produces Multiple Surface/Periplasmic Isoforms and mediates Adherence

The ability of Treponema pallidum, the syphilis spirochete to colonize various tissues requires the presence of surface-exposed adhesins that have been difficult to identify due to the inability to culture and genetically manipulate T. pallidum. Using a Borrelia burgdorferi-based heterologous system...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Chan, Kamfai, Nasereddin, Thayer, Alter, Laura, Centurion-Lara, Arturo, Giacani, Lorenzo, Parveen, Nikhat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861935/
https://ncbi.nlm.nih.gov/pubmed/27161310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25593
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