Muc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori binding

The gastrointestinal tract is lined by a thick and complex layer of mucus that protects the mucosal epithelium from biochemical and mechanical aggressions. This mucus barrier confers protection against pathogens but also serves as a binding site that supports a sheltered niche of microbial adherence...

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Udgivet i:Sci Rep
Main Authors: Magalhães, Ana, Rossez, Yannick, Robbe-Masselot, Catherine, Maes, Emmanuel, Gomes, Joana, Shevtsova, Anna, Bugaytsova, Jeanna, Borén, Thomas, Reis, Celso A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861914/
https://ncbi.nlm.nih.gov/pubmed/27161092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25575
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