Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery

In the human genome more than 400 genes encode ion channels, which are transmembrane proteins mediating ion fluxes across membranes. Being expressed in all cell types, they are involved in almost all physiological processes, including sense perception, neurotransmission, muscle contraction, secretio...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Imbrici, Paola, Liantonio, Antonella, Camerino, Giulia M., De Bellis, Michela, Camerino, Claudia, Mele, Antonietta, Giustino, Arcangela, Pierno, Sabata, De Luca, Annamaria, Tricarico, Domenico, Desaphy, Jean-Francois, Conte, Diana
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861771/
https://ncbi.nlm.nih.gov/pubmed/27242528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00121
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