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Co-evolving CENP-A and CAL1 Domains Mediate Centromeric CENP-A Deposition across Drosophila Species

Centromeres mediate the conserved process of chromosome segregation, yet centromeric DNA and the centromeric histone, CENP-A, are rapidly evolving. The rapid evolution of Drosophila CENP-A loop 1 (L1) is thought to modulate the DNA-binding preferences of CENP-A to counteract centromere drive, the pr...

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Publicat a:Dev Cell
Autors principals: Rosin, Leah, Mellone, Barbara G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861639/
https://ncbi.nlm.nih.gov/pubmed/27093083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.03.021
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