Streptococcus pyogenes Employs Strain-dependent Mechanisms of C3b Inactivation to Inhibit Phagocytosis and Killing of Bacteria

Evasion of complement-mediated opsonophagocytosis enables group A Streptococcus pyogenes (GAS) to establish infection. Different strain-dependent mechanisms are employed by the host to accomplish this goal. In general, GAS inhibits the amplification of the complement cascade on its cell surface by f...

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Vydáno v:J Biol Chem
Hlavní autoři: Agrahari, Garima, Liang, Zhong, Glinton, Kristofor, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861484/
https://ncbi.nlm.nih.gov/pubmed/26945067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704221
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