An Antibody Biosensor Establishes the Activation of the M(1) Muscarinic Acetylcholine Receptor during Learning and Memory

Establishing the in vivo activation status of G protein-coupled receptors would not only indicate physiological roles of G protein-coupled receptors but would also aid drug discovery by establishing drug/receptor engagement. Here, we develop a phospho-specific antibody-based biosensor to detect acti...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Butcher, Adrian J., Bradley, Sophie J., Prihandoko, Rudi, Brooke, Simon M., Mogg, Adrian, Bourgognon, Julie-Myrtille, Macedo-Hatch, Timothy, Edwards, Jennifer M., Bottrill, Andrew R., Challiss, R. A. John, Broad, Lisa M., Felder, Christian C., Tobin, Andrew B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861454/
https://ncbi.nlm.nih.gov/pubmed/26826123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681726
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki