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Molecular Circuitry of the SUMO (Small Ubiquitin-like Modifier) Pathway in Controlling Sumoylation Homeostasis and Suppressing Genome Rearrangements

Small ubiquitin-like modifier (SUMO) E3 ligases are known to have a major role in preventing gross chromosomal rearrangements (GCRs); however, relatively little is known about the role of SUMO isopeptidases in genome maintenance and their role in controlling intracellular sumoylation homeostasis. He...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: de Albuquerque, Claudio Ponte, Liang, Jason, Gaut, Nathaniel James, Zhou, Huilin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861450/
https://ncbi.nlm.nih.gov/pubmed/26921322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716399
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