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Regulation of drug-metabolizing enzymes by local and systemic liver injuries

INTRODUCTION: Drug metabolism and disposition are critical in maintaining the chemical and functional homeostasis of xenobiotics/drugs and endobiotics. The liver plays an essential role in drug metabolism and disposition due to its abundant expression of drug-metabolizing enzymes (DMEs) and transpor...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Metab Toxicol
Main Authors: Guo, Yan, Hu, Bingfang, Xie, Yang, Billiar, Timothy R., Sperry, Jason L., Huang, Min, Xie, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861312/
https://ncbi.nlm.nih.gov/pubmed/26751558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2016.1139574
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