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Homodimerization and constitutive activation of the erythropoietin receptor.

The erythropoietin receptor (EPO-R) is a member of the recently described cytokine receptor superfamily. A constitutively active (hormone independent) form of the EPO-R was isolated that has a single amino acid change in the exoplasmic domain, converting arginine-129 to cysteine (R129C). Since EPO-R...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Watowich, S S, Yoshimura, A, Longmore, G D, Hilton, D J, Yoshimura, Y, Lodish, H F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48612/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2140
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