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Homodimerization and constitutive activation of the erythropoietin receptor.

The erythropoietin receptor (EPO-R) is a member of the recently described cytokine receptor superfamily. A constitutively active (hormone independent) form of the EPO-R was isolated that has a single amino acid change in the exoplasmic domain, converting arginine-129 to cysteine (R129C). Since EPO-R...

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Autors principals: Watowich, S S, Yoshimura, A, Longmore, G D, Hilton, D J, Yoshimura, Y, Lodish, H F
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC48612/
https://ncbi.nlm.nih.gov/pubmed/1312714
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