A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway

Nitrilase1 was classified as a tumour suppressor in association with the fragile histidine-triad protein Fhit. However, knowledge about nitrilase1 and its tumour suppressor function is still limited. Whereas nitrilase1 and Fhit are discrete proteins in mammals, they are merged in Drosophila melanoga...

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Veröffentlicht in:Cell Discov
Hauptverfasser: Mittag, Sonnhild, Valenta, Tomas, Weiske, Jörg, Bloch, Laura, Klingel, Susanne, Gradl, Dietmar, Wetzel, Franziska, Chen, Yuan, Petersen, Iver, Basler, Konrad, Huber, Otmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860965/
https://ncbi.nlm.nih.gov/pubmed/27462437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.39
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