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Mapping gene regulatory circuitry of Pax6 during neurogenesis

Pax6 is a highly conserved transcription factor among vertebrates and is important in various aspects of the central nervous system development. However, the gene regulatory circuitry of Pax6 underlying these functions remains elusive. We find that Pax6 targets a large number of promoters in neural...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Discov
Hauptverfasser: Thakurela, Sudhir, Tiwari, Neha, Schick, Sandra, Garding, Angela, Ivanek, Robert, Berninger, Benedikt, Tiwari, Vijay K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860964/
https://ncbi.nlm.nih.gov/pubmed/27462442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.45
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