Selected SNARE proteins are essential for the polarized membrane insertion of igf-1 receptor and the regulation of initial axonal outgrowth in neurons

The establishment of polarity necessitates initial axonal outgrowth and, therefore, the addition of new membrane to the axon’s plasmalemma. Axolemmal expansion occurs by exocytosis of plasmalemmal precursor vesicles (PPVs) primarily at the neuronal growth cone. Little is known about the SNAREs famil...

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Bibliographic Details
Published in:Cell Discov
Main Authors: Grassi, Diego, Plonka, Florentyna Bustos, Oksdath, Mariana, Guil, Alvaro Nieto, Sosa, Lucas J, Quiroga, Santiago
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860833/
https://ncbi.nlm.nih.gov/pubmed/27462422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.23
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