Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

Specific BRAFV600E inhibitors (BRAFi) are highly effective in the treatment of melanoma. However, acquired drug resistances invariably develop after the initial response. Therefore, the identification of new mechanisms of acquired resistance gives important clues towards the development of therapies...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Discov
Asıl Yazarlar: Lehraiki, Abdelali, Cerezo, Michael, Rouaud, Florian, Abbe, Patricia, Allegra, Marilyne, Kluza, Jerome, Marchetti, Philippe, Imbert, Veronique, Cheli, Yann, Bertolotto, Corine, Ballotti, Robert, Rocchi, Stéphane
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860830/
https://ncbi.nlm.nih.gov/pubmed/27462428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.30
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