Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action

Soluble factors and cell-derived extracellular vesicles (EVs) control vascular cell fate during inflammation. The present study investigates the impact of Interleukin 3 (IL-3) on EV release by endothelial cells (ECs), the mechanisms involved in EV release and paracrine actions. We found that IL-3 in...

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Udgivet i:Sci Rep
Main Authors: Lombardo, Giusy, Dentelli, Patrizia, Togliatto, Gabriele, Rosso, Arturo, Gili, Maddalena, Gallo, Sara, Deregibus, Maria Chiara, Camussi, Giovanni, Brizzi, Maria Felice
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860593/
https://ncbi.nlm.nih.gov/pubmed/27157262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25689
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