Effects of hydrogen peroxide on voltage-dependent K(+) currents in human cardiac fibroblasts through protein kinase pathways

Human cardiac fibroblasts (HCFs) have various voltage-dependent K(+) channels (VDKCs) that can induce apoptosis. Hydrogen peroxide (H(2)O(2)) modulates VDKCs and induces oxidative stress, which is the main contributor to cardiac injury and cardiac remodeling. We investigated whether H(2)O(2) could m...

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Detalhes bibliográficos
Publicado no:Korean J Physiol Pharmacol
Main Authors: Bae, Hyemi, Lee, Donghee, Kim, Young-Won, Choi, Jeongyoon, Lee, Hong Jun, Kim, Sang-Wook, Kim, Taeho, Noh, Yun-Hee, Ko, Jae-Hong, Bang, Hyoweon, Lim, Inja
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860374/
https://ncbi.nlm.nih.gov/pubmed/27162486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.3.315
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