Effects of hydrogen peroxide on voltage-dependent K(+) currents in human cardiac fibroblasts through protein kinase pathways

Human cardiac fibroblasts (HCFs) have various voltage-dependent K(+) channels (VDKCs) that can induce apoptosis. Hydrogen peroxide (H(2)O(2)) modulates VDKCs and induces oxidative stress, which is the main contributor to cardiac injury and cardiac remodeling. We investigated whether H(2)O(2) could m...

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Publicat a:Korean J Physiol Pharmacol
Autors principals: Bae, Hyemi, Lee, Donghee, Kim, Young-Won, Choi, Jeongyoon, Lee, Hong Jun, Kim, Sang-Wook, Kim, Taeho, Noh, Yun-Hee, Ko, Jae-Hong, Bang, Hyoweon, Lim, Inja
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860374/
https://ncbi.nlm.nih.gov/pubmed/27162486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.3.315
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