NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts

Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart from ischemia-reperfusion injury. The aim of this study was to further define...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Korean J Physiol Pharmacol
Main Authors: Thu, Vu Thi, Kim, Hyoung Kyu, Long, Le Thanh, Thuy, To Thanh, Huy, Nguyen Quang, Kim, Soon Ha, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Format: Artigo
Jezik:Inglês
Izdano: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860373/
https://ncbi.nlm.nih.gov/pubmed/27162485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.3.305
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