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Microglial TNFα suppresses cocaine-induced plasticity and behavioral sensitization

Repeated administration of cocaine results in the development of behavioral sensitization, accompanied by a decrease in excitatory synaptic strength in the nucleus accumbens (NAc) through an unknown mechanism. Furthermore, glial cells in the NAc are activated by drugs of abuse, but the contribution...

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Bibliographic Details
Published in:Neuron
Main Authors: Lewitus, Gil M., Konefal, Sarah C., Greenhalgh, Andrew D., Pribiag, Horia, Augereau, Keanan, Stellwagen, David
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860141/
https://ncbi.nlm.nih.gov/pubmed/27112496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.03.030
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