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Thymic stromal lymphopoietin controls prostaglandin D(2) generation in aspirin-exacerbated respiratory disease

BACKGROUND: Prostaglandin D(2) (PGD(2)) is the dominant cyclooxygenase product of mast cells and is an effector of aspirin-induced respiratory reactions in aspirin-exacerbated respiratory disease (AERD). OBJECTIVE: We evaluated the role of the innate cytokine thymic stromal lymphopoietin (TSLP) acti...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Buchheit, Kathleen M., Cahill, Katherine N., Katz, Howard R., Murphy, Katherine C., Feng, Chunli, Lee-Sarwar, Kathleen, Lai, Juying, Bhattacharyya, Neil, Israel, Elliot, Boyce, Joshua A., Laidlaw, Tanya M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860132/
https://ncbi.nlm.nih.gov/pubmed/26691435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.10.020
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