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Hair cell stereociliary bundle regeneration by espin gene transduction after aminoglycoside damage and hair cell induction by Notch inhibition

Once inner ear hair cells (HCs) are damaged by drugs, noise or aging, their apical structures including the stereociliary arrays are frequently the first cellular feature to be lost. While this can be followed by progressive loss of HC somata, a significant number of HC bodies often remain even afte...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Taura, Akiko, Taura, Kojiro, Koyama, Yukinori, Yamamoto, Norio, Nakagawa, Takayuki, Ito, Juichi, Ryan, Allen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860107/
https://ncbi.nlm.nih.gov/pubmed/26886463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.12
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