Inflammatory signaling in human Tuberculosis granulomas is spatially organized

Granulomas are the pathological hallmark of tuberculosis (TB). However, their function and mechanisms of formation remain poorly understood. To understand the role of granulomas in TB, we analyzed the proteomes of granulomas from subjects with tuberculosis in an unbiased fashion. Using laser capture...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Marakalala, Mohlopheni J., Raju, Ravikiran M., Sharma, Kirti, Zhang, Yanjia J., Eugenin, Eliseo A., Prideaux, Brendan, Daudelin, Isaac B., Chen, Pei-Yu, Booty, Matthew G., Kim, Jin Hee, Eum, Seok Yong, Via, Laura E., Behar, Samuel M., Barry, Clifton E., Mann, Matthias, Dartois, Véronique, Rubin, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860068/
https://ncbi.nlm.nih.gov/pubmed/27043495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4073
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