Pre-fusion structure of a human coronavirus spike protein

HKU1 is a human betacoronavirus that causes mild yet prevalent respiratory disease(1), and is related to the zoonotic SARS(2) and MERS(3) betacoronaviruses, which have high fatality rates and pandemic potential. Cell tropism and host range is determined in part by the coronavirus spike (S) protein(4...

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Udgivet i:Nature
Main Authors: Kirchdoerfer, Robert N., Cottrell, Christopher A., Wang, Nianshuang, Pallesen, Jesper, Yassine, Hadi M., Turner, Hannah L., Corbett, Kizzmekia S., Graham, Barney S., McLellan, Jason S., Ward, Andrew B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860016/
https://ncbi.nlm.nih.gov/pubmed/26935699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17200
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