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Combatting synthetic designer opioids: active vaccination ablates lethal doses of fentanyl class drugs

Fentanyl is an addictive prescription opioid that is over 80 times more potent than morphine. The synthetic nature of fentanyl has enabled the creation of dangerous ‘designer drug’ analogues that escape toxicology screening, yet display comparable potency to the parent drug. Alarmingly, a large numb...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Bremer, Paul T., Kimishima, Atsushi, Schlosburg, Joel E., Zhou, Bin, Collins, Karen C., Janda, Kim D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860013/
https://ncbi.nlm.nih.gov/pubmed/26879590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511654
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