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Examining the transcriptional response of overexpressing anthranilate synthase in the hairy roots of an important medicinal plant Catharanthus roseus by RNA-seq

BACKGROUND: Clinically important anti-cancer drugs vinblastine and vincristine are solely synthesized by the terpenoid indole alkaloid (TIA) pathway in Catharanthus roseus. Anthranilate synthase (AS) is a rate-limiting enzyme in the TIA pathway. The transgenic C. roseus hairy root line overexpressin...

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Detalhes bibliográficos
Publicado no:BMC Plant Biol
Main Authors: Sun, Jiayi, Manmathan, Harish, Sun, Cheng, Peebles, Christie A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859987/
https://ncbi.nlm.nih.gov/pubmed/27154243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12870-016-0794-4
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