In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways

Tumor angiogenic process is regulated by multiple proangiogenic pathways, such as vascular endothelial growth factor receptor 2 (VEGFR2) and Axl receptor tyrosine kinase (Axl). Axl is one of many important factors involved in anti-VEGF resistance. Inhibition of VEGF/VEGFR2 signaling pathway alone fa...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Lei, Xueping, Chen, Minfeng, Nie, Qiulin, Hu, Jianyang, Zhuo, Zhenjian, Yiu, Anita, Chen, Heru, Xu, Nanhui, Huang, Maohua, Ye, Kaihe, Bai, Liangliang, Ye, Wencai, Zhang, Dongmei
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859888/
https://ncbi.nlm.nih.gov/pubmed/27186435
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