Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses

Subunit vaccines, employing purified protein antigens rather than intact pathogens, require the addition of adjuvants for enhanced immunogenicity with a correct balance between strong activation of the immune system and low toxicity. Here we show that the endogenous (i.e., autologous) non-toxic TLR4...

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Publicat a:Vaccine
Autors principals: Julier, Ziad, de Titta, Alexandre, Grimm, Alizée J., Simeoni, Eleonora, Swartz, Melody A., Hubbell, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859824/
https://ncbi.nlm.nih.gov/pubmed/27016652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.03.057
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