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Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo

Enhancers constitute one of the major components of regulatory machinery of metazoans. Although several genome-wide studies have focused on finding and locating enhancers in the genomes, the fundamental principles governing their internal architecture and cis-regulatory grammar remain elusive. Here,...

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Publicat a:eLife
Autors principals: Sayal, Rupinder, Dresch, Jacqueline M, Pushel, Irina, Taylor, Benjamin R, Arnosti, David N
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859806/
https://ncbi.nlm.nih.gov/pubmed/27152947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08445
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