C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer

T cell infiltration at the tumor site has been identified as a major predictor for the efficacy of adoptive T cell therapy. The chemokine C-C motif ligand 22 (CCL22) is highly expressed by immune cells in murine and human pancreatic cancer. Expression of its corresponding receptor, C-C chemokine rec...

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Publicado en:Oncoimmunology
Main Authors: Rapp, Moritz, Grassmann, Simon, Chaloupka, Michael, Layritz, Patrick, Kruger, Stephan, Ormanns, Steffen, Rataj, Felicitas, Janssen, Klaus-Peter, Endres, Stefan, Anz, David, Kobold, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859768/
https://ncbi.nlm.nih.gov/pubmed/27195186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1105428
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