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An additive effect of eplerenone to ACE inhibitor on slowing the progression of diabetic nephropathy in the db/db mice

Although blockade of the renin-angiotensin-system (RAS) has become standard therapy for diabetic nephropathy (DN), decline in kidney function towards end-stage renal disease is seen in many patients. Elevated plasma aldosterone often accompanies RAS blockade by a phenomenon known as “aldosterone esc...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Zhou, Guangyu, Johansson, Ulrika, Peng, Xiao-Rong, Bamberg, Krister, Huang, Yufeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859623/
https://ncbi.nlm.nih.gov/pubmed/27186263
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