Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

Microvascular hyperpermeability that occurs at the level of the blood-brain barrier (BBB) often leads to vasogenic brain edema and elevated intracranial pressure following traumatic brain injury (TBI). At a cellular level, tight junction proteins (TJPs) between neighboring endothelial cells maintain...

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Vydáno v:PLoS One
Hlavní autoři: Alluri, Himakarnika, Wilson, Rickesha L., Anasooya Shaji, Chinchusha, Wiggins-Dohlvik, Katie, Patel, Savan, Liu, Yang, Peng, Xu, Beeram, Madhava R., Davis, Matthew L., Huang, Jason H., Tharakan, Binu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859489/
https://ncbi.nlm.nih.gov/pubmed/27152411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154427
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